Publications

2024

• Structure-Based Design of Bicyclic Helical Peptides That Target the Oncogene β-Catenin. Yeste-Vázquez A, Paulussen FM, Wendt M, Klintrot R, Schulte C, Wallraven K, van Gijzel L, Simeonov B, van der Gaag M, Gerber A, Maric HM, Hennig S, Grossmann TN, 21 August 2024, In: Angewandte Chemie International Edition. DOI

• Full-length tRNAs lacking a functional CCA tail are selectively sorted into the lumen of extracellular vesicles. Scheepbouwer C., Aparicio-Puerta E., Gomez-Martin C., van Eijndhoven M.A.J. , Drees E.E.E. , Bosch L., de Jong D., Wurdinger T., Zijlstra J.M., Hackenberg M., Gerber A.*, Pegtel D.M.*, 12 May 2024, In: bioRxiv. *corresponding authors. DOI

• The choreography of chromatin in RNA polymerase III regulation. van Breugel M.E., Gerber A., van Leeuwen F., 26 April 2024, In: Biochemical Society Transactions. DOI

2023

• NORMSEQ: a tool for evaluation, selection and visualization of RNA-Seq normalization methods. Scheepbouwer, C., Hackenberg, M., van Eijndhoven, M.A.J., Gerber A., Pegtel D.M., Gómez-Martín, C., 22 May 2023, In: Nucleic Acids Research. Online ahead of print. p.1-7. DOI

• Bicyclic Engineered Sortase A Performs Transpeptidation under Denaturing Conditions. Kiehstaller S., Hutchins G.H., Amore A., Gerber A., Ibrahim M, Hennig S, Neubacher S, Grossmann TN., 21 Jun 2023. In: Bioconjugate Chemistry. 34(6):1114-1121. DOI 

• Understanding spatiotemporal coupling of gene expression using single molecule RNA imaging technologies. Gerber, A., van Otterdijk, S., Bruggeman, F.J., Tutucc,i E., 12 April 2023, In: Transcription. Online ahead of print. p.1-22. DOI

• ALL-tRNAseq enables robust tRNA profiling in tissue samples. Scheepbouwer, C., Aparicio-Puerta, E., Gomez-Martin, C., Verschueren, H., van Eijndhoven, M., Wedekind, L. E., Giannoukakos, S., Hijmering, N., Gasparotto, L., van der Galien, H. T., van Rijn, R. S., Aronica, E., Kibbelaar, R., Heine, V. M., Wesseling, P., Noske, D. P., Vandertop, W. P., de Jong, D., Pegtel, D. M., Hackenberg, M., Wurdinger, T., Gerber, A. & Koppers-Lalic, D., 21 Feb 2023, In: Genes & Development. Published in Advance. DOI

2022

• Inhibitors of the Wnt Signaling Pathway and Uses Thereof. Grossmann, T. N., Wendt, M., Efrém, N. L., Bellavita, R., van Ramshorst, T. & Gerber, A.. 22 Mar 2022, Patent appl. WO/2022/203510. EP 4063380 A1 

2021

• Bicyclic β-Sheet Mimetics that Target the Transcriptional Coactivator β-Catenin and Inhibit Wnt Signaling. Wendt, M., Bellavita, R., Gerber, A., Efrém, N. L., van Ramshorst, T., Pearce, N. M., Davey, P. R. J., Everard, I., Vazquez-Chantada, M., Chiarparin, E., Grieco, P., Hennig, S. & Grossmann, T. N., 14 Jun 2021, In: Angewandte Chemie - International Edition. 60, 25, p. 13937-13944 8 p. DOI

• Critical roles of transcriptional coactivator MED1 in the formation and function of mouse adipose tissues. Ito, K., Schneeberger, M., Gerber, A., Jishage, M., Marchildon, F., Maganti, A. V., Cohen, P., Friedman, J. M. & Roeder, R. G., 1 May 2021, In: Genes & Development. 35, 9-10, p. 729-748 20 p. DOI

2020

• The CTD Is Not Essential for the Post-Initiation Control of RNA Polymerase II Activity. Gerber, A.* & Roeder, R. G.*, 21 Jul 2020, In : Journal of Molecular Biology. 432, 19, p. 5489-5498. *corresponding authors. DOI

• Functions of paralogous RNA polymerase III subunits POLR3G and POLR3GL in mouse development. Wang, X., Gerber, A., Chen, W-Y. & Roeder, R. G., 23 Jun 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 27, p. 15702-15711. DOI

• Gene-Specific Control of tRNA Expression by RNA Polymerase II. Gerber, A.*, Ito, K., Chu, C. S. & Roeder, R. G.*, 21 May 2020, In : Molecular Cell. 78, 4, p. 765-778 14 p. *corresponding authors. DOI

• A histone-like motif in yellow fever virus contributes to viral replication. Mourao, D., Chen, S., Schaefer, U., Bozzacco, L., Carneiro, L. A., Gerber, A., Adura, C., Dill, B. D., Molina, H., Carroll, T., Paul, M., Bhanu, N. V., Garcia, B. A., Joberty, G., Rioja, I., Prinjha, R. K., Roeder, R. G., Rice, C. M., MacDonald, M. R., Patel, D. J. & Tarakhovsky A., In : bioRxiv. 6 May 2020. DOI

2019

• Induced RPB1 depletion reveals a direct gene-specific control of RNA Polymerase III function by RNA Polymerase II. Gerber, A.*, Ito, K., Chu, C-S. & Roeder, R. G.*, In : bioRxiv. 10 Sep 2019. *corresponding authors. DOI

2017

• Diurnal Oscillations in Liver Mass and Cell Size Accompany Ribosome Assembly Cycles. Sinturel, F., Gerber, A., Mauvoisin, D., Wang, J., Gatfield, D., Stubblefield, J. J., Green, C. B., Gachon, F. & Schibler, U., 4 May 2017, In : Cell. 169, 4, p. 651-663.e14. DOI

2016

• Clock-Talk: Interactions between central and peripheral circadian oscillators in mammals. Schibler, U., Gotic, I., Saini, C., Gos, P., Curie, T., Emmenegger, Y., Sinturel, F., Gosselin, P., Gerber, A., Fleury-Olela, F., Rando, G., Demarque, M. & Franken, P., 1 Jan 2016, 21st Century Genetics Genes at Work, 2015. Grodzicker, T., Stillman, B. & Stewart, D. (eds.). Cold Spring Harbor Laboratory Press, p. 223-232 10 p. (Cold Spring Harbor Symposia on Quantitative Biology; vol. 80). DOI

2015

• The systemic control of circadian gene expression. Gerber, A., Saini, C., Curie, T., Emmenegger, Y., Rando, G., Gosselin, P., Gotic, I., Gos, P., Franken, P. & Schibler, U., 1 Sep 2015, In : Diabetes, Obesity and Metabolism. 17, S1, p. 23-32 10 p. DOI

2013

• Blood-borne circadian signal stimulates daily oscillations in actin dynamics and SRF activity. Gerber, A., Esnault, C., Aubert, G., Treisman, R., Pralong, F. & Schibler, U., 31 Jan 2013, In : Cell. 152, 3, p. 492-503 12 p. DOI

Prior to 2013

• The pollutant diethylhexyl phthalate regulates hepatic energy metabolism via species-specific PPARα-dependent mechanisms. Feige, J. N., Gerber, A., Casals-Casas, C., Yang, Q., Winkler, C., Bedu, E., Bueno, M., Gelman, L., Auwerx, J., Gonzalez, F. J. & Desvergne, B., 1 Feb 2010, In : Environmental Health Perspectives. 118, 2, p. 234-241 8 p. DOI

• Modulators of Cell Adhesion Molecules and Use Thereof. Ossipow, V., Pellissier, F., Gerber, A. & Ballivet, M., 8 May 2008, Patent appl. WO/2008/053049. EP 1918299 A1 

• The adhesion molecule Necl-3/SynCAM-2 localizes to myelinated axons, binds to oligodendrocytes and promotes cell adhesion. Pellissier, F., Gerber, A., Bauer, C., Ballivet, M. & Ossipow, V., 29 Oct 2007, In : BMC Neuroscience. 8, 90. DOI